Macrolide prescriptions and erythromycin resistance of Streptococcus pyogenes.
نویسندگان
چکیده
This study shows a significant association between the number of macrolide prescriptions reimbursed by the Italian National Health Service and resistance of Streptococcus pyogenes to erythromycin in children from a region in northern Italy with high prevalence of erythromycin resistance. Recent prescription of a macrolide (especially azithromycin) is a predictor of erythromycin resistance, as well as a possible risk factor for resistance at a community level.
منابع مشابه
A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes.
Streptococcus pyogenes is the major bacterial pathogen responsible for acute pharyngitis in children. Oral penicillin is the drug of choice for streptococcal pharyngitis, while macrolides are an alternative option for patients allergic to penicillin. The frequent use of macrolides promotes the spread of erythromycin resistance (1-2), but reducing the use of these antibiotics has been correlated...
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ورودعنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 42 8 شماره
صفحات -
تاریخ انتشار 2006